Molecular Characterization of Norovirus and Rotavirus in Outbreak of Acute Gastroenteritis in Seoul.
10.4167/jbv.2013.43.4.307
- Author:
Se Ah OH
1
;
Sang Hun PARK
;
Hee Jin HAM
;
Hyun Jung SEUNG
;
Jung Im JANG
;
Sang Won SUH
;
Suk Ju JO
;
Sung Min CHOI
;
Hae Sook JEONG
Author Information
1. Seoul Metropolitan Government Research Institute of Public Health and Environment, Virus team, 202-3, Yangjae-Dong, Seocho-Gu, Seoul, Korea. sea02@seoul.go.kr
- Publication Type:Original Article
- Keywords:
Norovirus;
Rotavirus;
Genotypes;
Gastroenteritis outbreak
- MeSH:
Diarrhea;
Enzyme-Linked Immunosorbent Assay;
Gastroenteritis*;
Genotype;
Humans;
Korea;
Norovirus*;
Public Health;
Rotavirus*;
Seoul*
- From:Journal of Bacteriology and Virology
2013;43(4):307-316
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Norovirus and rotavirus are important causes of acute nonbacterial gastroenteritis in communities worldwide. Genotypes of norovirus and rotavirus in stool samples, which were collected from patients, was determined by RT-PCR and ELISA. A total 4,484 stool samples (461 outbreak cases) collected during January 2010-April 2013 were analyzed. Four hundred thirty eight of samples were positive for norovirus. Twelve samples were positive for Rotavirus. Norovirus genotypes identified were nine kinds of G I genotype (G I -1, G I -2, G I -3, G I -4, G I -6, G I -7, G I -9, G I -12, G I -13) and nine kinds of G II genotype(G II -2, G II -4, G II -5, G II -6, G II -7, G II -11, G II -12, G II -15, G II -16). Rotavirus genotypes were G2P[4]. The results might be useful information for evaluating the epidemiological status of viral diarrhea in Seoul, and providing a strategy to prevent human norovirus, rotavirus and other threats to public health in Korea.