Androgen hormones metabolism and heart vascular disesase
- VernacularTitle:Эрэгтэйчүүдийн андроген гормоны солилцоо ба зүрх судасны өвчин
- Author:
Bayaraa T
1
;
Sodgerel B
1
;
Badamsed TS
1
;
Purevsuren D
1
;
Galsumiya L
1
;
Achitmaa M
1
;
Surenjav CH
1
Author Information
1. Institute of Medical Sciences Named after acad. T.Shagdarsuren
- Publication Type:Journal Article
- Keywords:
age-related hypogonadism;
risk factors;
cardiovascular diseases;
hormone replacement therapy;
- From:Mongolian Medical Sciences
2017;179(1):52-59
- CountryMongolia
- Language:Mongolian
-
Abstract:
Article deals with age-related hypogonadism in men as an interdisciplinary problem. Current definition, prevalence, analyzes the relationship between age and the incidents of hypogonadism were shown. The detailed overview of clinical studies, meta analysis of causal link of androgen deficiency and erectile dysfunction, ischemic heart disease, arterial hypertension, dyslipidemia, and diabetes mellitus was presented. To date was found the relationship between metabolic syndrome and androgen deficiency. Low level of testosterone is closely connected with low libido as well as insulin resistance, abdominal obesity, dyslipidemia. Insulin resistance and hyperinsulinemia are noticed in patients with hypogonadism in comparison with obese and normal-weight patients. Therefore, metabolic risk factors are the connecting link of cardiovascular diseases and androgen deficiency. Meta-analysis of clinical trials of the effects of testosterone replacement therapy and safety of long term use was presented in the article. The article discusses the importance of a unified approach to the diagnosis and treatment of androgen-deficient conditions and cardiovascular disease.
- Full text:2017-179(1)-52-59.pdf
