Urinary bladder cancer diagnosed by pathologic method
- VernacularTitle:Давсагны хавдрыг эмгэг судлалын аргаар оношлосон нь
- Author:
Bolortuya B
1
;
Bayarmaa E
;
Galtsog L
Author Information
1. Pathology Center
- Publication Type:Journal Article
- Keywords:
urinary bladder cancer;
urothelial carcinoma;
histological classification
- From:Mongolian Medical Sciences
2010;152(2):12-15
- CountryMongolia
- Language:Mongolian
-
Abstract:
BACKGROUND: Urinary bladder cancer (UBC) ranks ninth in worldwide cancer incidence. It is the seventh most commonmalignancy in men and seventeenth in women. UBC tends to occur most commonly in individuals over 65 orolder men and the male to female ratio are 3:1. The vast majority (over 90%) of bladder cancers are transitionalcell or urothelial carcinoma. Many experts did favor the 1998 World Health Organization/international Societyof Urological Pathology (WHO/ISUP) formulation for urothelial neoplasm. The 2004 WHO had accepted thenomenclature used in 1998, the system is currently used in countries of the world. Histology is the gold standardof typing, grading and staging to determine prognosis of the disease and process tactics of treatment. This newclassification system is not been introduced in our country yet, so UBCs are still formulated with the WHO 1973system. And there are no noted studies for UBC yet in Mongolia, these reasons were the background to determinethe UBC pathology with international classification system and nature of UBC in Mongolians.OBJECTIVE: To classify urinary bladder cancer occurred in Mongolia with the current histological classification and determinesspecific characters of pathology.MATERIALS AND METHODS: In this study we evaluated 138 patients with UBC diagnosed in Urological department of Central UniversityHospital, biopsy materials of these patients are classified with WHO/ISUP(2004) and results were analyzed.RESULT: Of the 108 patients with urinary bladder tumor, 2 patients (2%) were diagnosed with papilloma, 13 patients (12%)with papillary urothelial neoplasm of low malignant potential, 93 patients (86%) diagnosed with UC. Of 93 patientswith bladder carcinoma, majority of patients (91/98%) were diagnosed with urothelial carcinoma, 2 patients (2%)were diagnosed with adenocarcinoma. 74 (79.5%) of study patients were male, 19 (20.5%) were female and themale to female ratio was 3.9:1. Older man (over 50) was 65 (88%). Of UC (91), 1(1%) was carcinoma in situ,38 (42%) low grade papillary carcinoma, 33 (36%) high grade papillary carcinoma, 19 (21%) were no papillaryurothelial carcinoma. Of bladder carcinoma (93), 29 (31%) were superficial cancer (pTa, pTis), 58 (62%) wereinvasive cancer (pT₁₋₄).CONCLUSION: Urinary bladder cancer is in the majority in urinary bladder tumor in our country and transitional cell or urothelialcarcinoma compresses 98%. The male to female ratio in patients with bladder carcinoma is 3.9:1, older men over50 years are overweening affected.
