Early diagnosis of nephropathy in patients with hypertension
- VernacularTitle:Артерийн даралт ихдэлтийн шалтгаант бөөрний эмгэгийн эрт үеийн оношлогоо
- Author:
Naran-Ulzii S
1
;
Ariunaa T
;
Baigalmaa E
;
Ariuntsetseg N
;
Enkhtuya J
Author Information
1. Central Clinical Hospital for State Special Clerks
- Publication Type:Journal Article
- Keywords:
early diagnosis;
glomerular filtration rate;
hypertension;
nephropathy
- From:Mongolian Medical Sciences
2011;172(2):45-49
- CountryMongolia
- Language:Mongolian
-
Abstract:
Background: High blood pressure is both a cause and a complication of chronic kidney disease. As complication, high blood pressure may develop early during course of chronic kidney disease and is associated with adverse outcomes, in particular faster loss of kidney function and development of cardiovascular disease. The purpose of this study is early detection of chronic kidney disease in patients with hypertension by defining the prevalence of microalbuminuria.Methods: The study population consisted of 169 subjects with a hypertension. Individuals were considered to have hypertension if the blood pressure measured greater than 140/90 mmHg or if they were taking blood pressure lowering medications. Microalbuminuria was defined as 20 mg/l or greater. Results: We are presenting data on 169 subjects :male 38 (22.5%) female 131 (77.5%), average age 51.6±0.89 At screening, 14.8% of all participants were smokers, 62.1 % engaged in low levels of physical activity, 72.8% - were having tea with salt (table1). Microalbuminuria and renal failure, as GFR<60 ml/ min/1.73 m2, were documented in 34.3% and 16.6% of subjects, respectively. There is positive correlation between MAU and increasing-range of blood pressure (table2). Correlation was found between albuminuria and GFR(r= -0.2 p<0.01) and serum creatinine(r=0.31 p<0.01) the regression result has shown that GFR is associated with MAU and serum creatinine (table 3).Conclusions:1. In 34.3% of patient with hypertension was found nephropathies with MAU2. Microalbuminuria is increased with decline of GFR and raise of systolic blood pressure. GFR decline is with the raise of age and serum. It is important to implement in clinical practice screening of MAU hypertensive patients.3. In 2/3 of all screened subjects was found 1 and more risk factors for CVD.
