Advance in Research on Brain Protection Mechanisms of Fastigial Nucleus Stimulation (review)
- VernacularTitle:小脑顶核刺激脑保护机制研究进展
- Author:
Mujiang ALI
;
Runfeng ZHANG
;
Dayi HU
- Publication Type:Journal Article
- Keywords:
cerebellum, fastigial nucleus, electrical stimulation, review
- From:
Chinese Journal of Rehabilitation Theory and Practice
2007;13(8):718-720
- CountryChina
- Language:Chinese
-
Abstract:
The research on fastigial nucleus could be traced back to 19th century. However the great achievements on cerebrum overshadowed the importance of cerebellum and its nucleus. In recent 30 years, with the finding of brain protection effect of fastigial nucleus stimulation, much attention has been given to this field. Now its widely accepted that electrical stimulation of fastigial nucleus has brain protection effect and concrete mechanisms can be concluded as: improving the electrical instability around the infarct zone, reducing peri-infarction depolarizing wave and cortical spreading depression; suppressing microvessels inflammatory reaction; inhibiting cell apoptosis; reducing the neurons damage and facilitates neovascularization and so on. These new discoveries was reviewed and further expectation on this field was put forward by the authors.
