Effect of Percutaneous Autogenous Bone Marrow Stem Cell Transplant on Bone Nonunion
- VernacularTitle:经皮自体骨髓干细胞移植治疗骨不连的临床研究
- Author:
Jinguo YUAN
;
Mingke YU
;
Zhiling ZHOU
;
Zhenan ZHU
- Publication Type:Journal Article
- Keywords:
bone marrow stem cell, autotransplantation, bone nonunion, fracture
- From:
Chinese Journal of Rehabilitation Theory and Practice
2007;13(7):661-662
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical effect of percutaneous autogenous bone marrow stem cell transplant on bone nonunion. Methods 140 patient with bones nonunion were divided into the autogenous bone transplants (A) group and the autogenous bone marrow stem cell transplant (B) group, with 70 cases in each group. They were assessed 2 and 5 months after operation. Results A few calluses could be observed at the end of fracture in 42 cases in group A 2 months after operation, and massive callus formation could be observed in 46 cases 5 months after operation. However, massive callus formation could be observed in 60 cases in group B 2 months after operation, and continual callus formation could be observed in 45 cases 5 months after operation. The mean healing time was (8.4±1.8) months in group A, and (6.5±2.0) months in group B (P<0.05). No side-effects have been observed during the treatment. Conclusion The percutaneous autogenous bone marrow stem cell transplant is more effective on bone nonunion compared with the traditional treatment.
