Isolated compounds from Saxifraga Spinulosa and their antioxidative activity
- VernacularTitle:Шивүүрт сэрдэг(Saxifraga Spinulosa Adams)-ийн антиоксидант идэвхт нэгдлийн судалгаа
- Author:
Duger Badral
1
;
Toshihiro Murata
2
;
Gendaram Odontuya
3
;
Javzan Batkhuu
4
Author Information
1. Mongolian University of Pharmaceutical Sciences
2. Department of Pharmacognosy, Tohoku Medical and Pharmaceutical University, Aoba-ku, Sendai 981-8558, Japan
3. Natural Product Chemistry Laboratory, Institute of Chemistry and Chemical Technology, Mongolian Academy of Sciences
4. School of Engineering and Applied Sciences, National University of Mongolia
- Publication Type:Journal Article
- From:
Mongolian Pharmacy and Pharmacology
2021;18(1):64-68
- CountryMongolia
- Language:Mongolian
-
Abstract:
Abstract:The genus Saxifraga, one of the largest genera of the Saxifragaceae family, comprises 540 species and is distributed widely in mountainous and rocky regions, with 12 species being found in Mongolia. Saxifraga spinulosa Adams is a perennial herbaceous plant common in mainland China, Russia, and Mongolia, inhabiting stony marginal terrain. The isolated compounds from Saxifraga spinulosa were screened for DPPH radical-scavenging activity, with Trolox as a positive control (IC50 23.3 µM). All the new glucosides exhibited potent activities (IC50 19.0–72.9 µM). A crude ex- tract of S. spinulosa has been reported to display the highest DPPH radical-scavenging activity among numerous Mongolian medicinal plants, which may now be attributed, at least in part, to the presence of the new flavonoid and galloyl group-containing isolated compounds.
- Full text:MPPJ-2021-18(1)-64-68.pdf
