Effects of Srog dzin-5 prescription on pathogenesis model of acute stress and animal models of depressive disorders
- VernacularTitle:Амьтанд үүсгэсэн цочмог стресс, сэтгэл төст авир төрхийн эмгэг загварт Амь баригч-5 жорын үзүүлэх нөлөө
- Author:
Altantuya Ts
1
;
Tsetsegmaa S
2
;
Bold Sh
3
Author Information
1. Mongolian University of Pharmaceutical Sciences
2. Institute of Pharmacology
3. Mongolian Academy of Sciences
- Publication Type:Journal Article
- Keywords:
traditional Mongolian medicine;
Srog dzin-5;
prescription;
depressive disorders
- From:
Mongolian Pharmacy and Pharmacology
2020;17(2):79-87
- CountryMongolia
- Language:Mongolian
-
Abstract:
Abstract:There is a growing need for a systematic study of the use of medicines prepared from herbal, animal, and mineral raw materials in traditional Mongolian medicine to a new level. Based on traditional medicine technology and use, the study identified the most suitable modern medicinal ingredients for the human body, namely a medicine that can be used for depression in the ancient scripture, “Ngo mtshar dga’ ston gter mdzod” by Gelen Choijamts and further practical application is imperative.
Purpose:To study the effects of Srog dzin-5 prescription on pathogenesis model of acute stress and animal models of depressive disor- ders.
Conclusion:1. In the pathogenesis model of acute stress disorder caused by restricted mobility, Srog dzin-5 prescription prevents stress-induced thymic involution and enlargement of adrenal glands.
2. In the pathogenesis model of ethanol-induced depression, Srog dzin-5 prescription increased physical activity, reduced despair, and prevented anxiety according to behavioral assessment.
- Full text:MPPJ-2020-17(2)-79-87.pdf
