Role of Neurotrophins and Immune Molecules in the Repair of the Central Nervous System (review)
- VernacularTitle:神经营养因子和免疫分子在中枢神经系统修复中的作用
- Author:
Chong-ran SUN
;
Jin LI
;
Han ZHANG
;
Hua HUANG
;
Yihua AN
;
Zhongcheng WANG
- Publication Type:Journal Article
- Keywords:
neurotrophins, immune response, immune molecules, neural repair, review
- From:
Chinese Journal of Rehabilitation Theory and Practice
2006;12(8):659-660
- CountryChina
- Language:Chinese
-
Abstract:
Neurotrophins promote and modulate the repair and regeneration of central nervous system (CNS) on the levels of synapses, neurites and neural cells, and even of the auxiliary structures of CNS. As to immune molecules, recent studies denied the classical doctrine that CNS is an immune privilege organ. In the last decade, it is found that immune responses can be beneficial for CNS repair. What are more, some macromolecules that were previously thought to be the members of the family of immune system play essential roles in the development and regeneration of the CNS. Therefore, the authors postulate that there are crosstalks between the neurotrophins and the immune molecules in the CNS.
