Long-term Effect of Different Antihypertensive Agents on Renal Hemodynamics
- VernacularTitle:不同类型降压药物对肾内血流动力学长期影响的研究
- Author:
Zhi-qing FU
;
Liao-sheng ZHOU
;
Rui XU
;
Huaqing ZHANG
;
Qing WANG
;
Xiaoying LI
- Publication Type:Journal Article
- Keywords:
essential hypertension, renal function, antihypertensive agent, renal blood flow
- From:
Chinese Journal of Rehabilitation Theory and Practice
2006;12(7):606-607
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo investigate the long term effect of different antihypertensive agents on renal hemodynamics with ultrasound Doppler.Methods52 essential hypertensive patients were divided into three groups according to the antihypertensive agent they took: angiotensin-converting-enzyme inhibitor (ACEI), calcium channel blocker (CCB) and β-adrenoceptor blocker (βB). The blood pressures of right upper arms were measured with mercury column blood pressure gauge using Korotkoff method. Renal hemodynamics were examined with ultrasound Doppler before and after treatment with agents. ResultsSystolic blood pressure (SBP) and diastolic blood pressure (DBP) of all patients were decreased significantly. An significant correlation was found between the deceases of blood pressure and the betterment of renal homodynamic parameters in ACEI and CCB groups, but not in βB group. ConclusionTo a degree, the betterment of renal hemodynamics is correlation with the reduction of systemic blood pressure and mechanism of action of antihypertensive agents.
