A review on traditional usage, phytochemical composition and biological activity of Pedicularis L.
- VernacularTitle:Хувилангын (pedicularis l.) Зүйл ургамлуудын уламжлалт анагаах ухааны хэрэглээ ба фитохими, биологийн идэвхийн судалгааны тойм
- Author:
Nyamsuren E
1
;
Odontuya G
1
Author Information
1. Institute of Chemistry and Chemical Technology, MAS
- Publication Type:Journal Article
- Keywords:
Pedicularis L.;
lug-ru;
phytochemical constituents;
biological activities
- From:
Mongolian Pharmacy and Pharmacology
2018;13(2):5-13
- CountryMongolia
- Language:Mongolian
-
Abstract:
Introduction:Plant species of Pedicularis L., one of the largest genera of the Scrophulariaceae family, is found in cold regions of Asia, Europe, and America. In ancient Chinese, Tibetan, and
Indian medicinal literature, it is noted that due to the detoxification potential of Pedicularis L., it has
been used for reducing and curing of edema, fever, inflammation and poisoning. In the recent studies, species of Pedicularis L. have been determined to possess anti-oxidative, antitumor, antibacterial, antifatigue and, analgesic activities, as well as muscle relaxant, hepatoprotective effects. From
this genus, more than 230 constituents, mostly belonging to the phenylpropanoids, iridoids, lignans
and their glycosides have been isolated and identified.
Material and method:In this review, we reviewed 80 papers on the genus Pedicularis L.
which were published in scientific journals from 1963 to 2018, using databases such as Springer
Link, Google Scholar, Pub Med, Elsevier, Research Gate. In addition, literatures on Mongolian medicinal plants and herbal medicines have been used, where the taxonomy, morphology of Pedicularis
L. and their usage was described.
Conclusions:As this survey, less than 10 percent of the 600 species of Pedicularis L. has
been studied for their phytochemical constituents and biological activities. More than 230 compounds
including phenylpropanoids, iridoids, lignans, flavonoids, alkaloids and other classes of constituents
have been isolated and their molecular structures were identified. Among them, 67 compounds or 30
percent were natural new compounds. Anti-oxidative, antibacterial, antitumor and, muscle relaxant
activities of the Pedicularis L. related to the quantities and structural peculiarities of phenylpropanoid
glycosides, iridoid glycosides, and flavonoids. Especially, phenylpropanoid glycosides are more interesting as they demonstrate wide range and much higher biological activity compared to other
classes of compounds. Therefore, future research will focus on chemistry and biological activity of
this class of compounds.
- Full text:MPPJ-2018-13(2)-5-13.pdf
