Experimental Study on Prevention of Post-surgical Abdominal Adhesions by Medical Chitin Degraded Membrane
- VernacularTitle:粘停宁预防外科术后腹腔粘连的实验研究
- Author:
Xin SHEN
;
Meng-bin LI
;
Wei-zhong WANG
;
Hai SHI
- Publication Type:Journal Article
- Keywords:
surgery, adhesions, peritoneum, medical chitin degraded membrane, postoperative complication, rabbit
- From:
Chinese Journal of Rehabilitation Theory and Practice
2006;12(7):581-582
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo investigate the effects of medical chitin degraded membrane on post-surgical abdominal adhesions.MethodsForty adult rabbits were made to form abdominal adhesions and divided randomly into four groups including group A1 and its control group A2, group B1 and its control groups B2 with 10 animals in each group. Medical chitin degraded membrane was applied in the group A and group B to the surfaces of the positions where would be adhered. All animals were cut the belly open again on the 7th, 14th postoperative day; the adhesions about incision and appendix were graded according to the severity, and took on bioscopy.ResultsThe abdominal adhesions model was successful. The severity of adhesions and inflammatory reaction of the group A1 and group B1 was significantly milder than that of the group A2 and group B2 in every different periods ( P<0.05).ConclusionThe medical chitin degraded membrane used intraoperatively might have some efficacy in preventing post-surgical abdominal adhesions.
