Research progress on effective components，pharmacological mechanisms and clinical use of Polyporus umbellatus in diuresis-promotion and dampness-clearance
- VernacularTitle:猪苓利水渗湿的药效物质、药理作用机制及临床应用研究进展
- Author:
Wenjing LU
1
;
Hui REN
1
;
Xiaomin CUI
1
;
Jing HU
1
;
Tong QU
1
;
Ning LI
1
;
Zhiyong CHEN
1
Author Information
1. Shaanxi Academy of Traditional Chinese Medicine，Xi’an 710003，China
- Publication Type:Journal Article
- Keywords:
Polyporus umbellatus;
diuresis-promotion and dampness-clearance;
effective components;
steroids;
Polyporus
- From:
China Pharmacy
2023;34(11):1399-1403
- CountryChina
- Language:Chinese
-
Abstract:
Polyporus umbellatus， as a traditional Chinese medicine for promoting diuresis and clearing dampness， mainly contains steroids and polysaccharides. It is usually used to treat diseases of urinary system. In this paper， the research progress of the effective components， pharmacological mechanisms and clinical use of P. umbellatus in diuresis-promotion and dampness- clearance is reviewed. Steroids such as ergosterone， peroxyergosterone， ergosta-7，22-dien-3-one and P. umbellatus polysaccharide PPS1， PPS2， PPS3， GUMP-1-1 and GUMP-1-2 promote diuresis and eliminate dampness through diuresis， renal protection， anti- inflammatory， bacteriostatic and immunomodulatory effects. Traditional Chinese medicine compound preparations such as P. umbellatus powder， P. umbellatus decoction， and Wuling powder have significant effects in treating urinary tract infections， lithiasis， renal edema and lesions， which providing reference for the further development and application of P. umbellatus.
