Quality analysis of Codonopsis pilosula with different commodity specification grades
- VernacularTitle:不同商品规格等级党参药材的质量分析
- Author:
Xiaohui ZHANG
1
;
Liguo TONG
1
;
Yibing WANG
2
;
Zhiqiang LI
3
;
Xiaohu XI
3
;
Shuang WANG
3
;
Shiwei WANG
3
Author Information
1. Central Laboratory，Shanxi Academy of Traditional Chinese Medicine，Taiyuan 030012，China
2. Dept. of Pharmacy，Changzhi Medical College，Shanxi Changzhi 046013，China
3. Dept. of Pharmacy，Shanxi Hospital of Traditional Chinese Medicine，Taiyuan 030012，China
- Publication Type:Journal Article
- Keywords:
Codonopsis pilosula;
commodity specification
- From:
China Pharmacy
2023;34(11):1363-1367
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To study the quality of Codonopsis pilosula with different commodity specification grades， and to provide the data support for market transactions， scientific research and clinical use. METHODS According to the classification standard of commodity specification grades of C. pilosula， 17 batches of C. pilosula from different producing areas， origins and commodity specification grades were collected. The contents of tangshenoside Ⅰ， lobetyolin and atractylenolide Ⅲ were determined by HPLC. The contents of alcohol-soluble extracts were determined by hot dipping method stated in general rule 2201 of Chinese Pharmacopeia （part Ⅳ）. The contents of polysaccharide were determined by phenol-sulfuric acid method （calculated by D-glucose anhydrous）. RESULTS For cultivar of C. pilosula， four specifications and three commodity grades of C. pilosula all contained tangshenoside Ⅰ and lobetyolin； Radix C. pilosula from Shanxi of China and C. pilosula from Wenxian County of China， also contained atractylenolide Ⅲ. In terms of the contents of tangshenoside Ⅰ， lobetyolin and atractylenolide Ⅲ， the content of second class was equivalent to that of first class， even better than the first class， while the content of third class was lower than that of first class and second class； the content of tangshenoside Ⅰ was the highest among the two types of wild C. pilosula. The contents of alcohol-soluble extracts and polysaccharides in first class cultivated C. pilosula were higher than those of second class， and the second class was higher than the third class； wild C. pilosula had low content of alcohol-soluble extracts and polysaccharides. CONCLUSIONS The internal quality of C. pilosula is basically consistent with the classification standard of different commodity specification grades； the content of each indicator in first-class and second-class medicinal herb is high， making them high-quality medicinal herbs.
