Clinical Analysis on 425 Cases of POEMS Syndrome
- VernacularTitle:POEMS综合征425例临床分析
- Author:
Hai-hui WANG
;
Wei YAN
;
Bing CHEN
;
Haitao GUO
;
Fuhua WANG
- Publication Type:Journal Article
- Keywords:
POEMS syndrome, peripheralneuropathy, myeloma
- From:
Chinese Journal of Rehabilitation Theory and Practice
2006;12(6):527-528
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo summarize the clinical features of reported 425 domestic cases of POEMS syndrome, and its diagnosis and treatment.MethodsClinical characteristics of 425 POEMS cases were summarized with meta analysis.ResultsPOEMS syndrome usually occurred in middle-age males, and its onset age ranged from 11 to 74 years, averaged 43 years. Clinical display was characterized by a combination of polyneuropathy, organomegaly, endocrinopathy, M-protein and skin changes. It usually occurred with osteomyeloma. Most patients died of serious infections, respiratory insufficiency or heart failure. The treatment with glycocorticosteroid had led to short-time improvement.ConclusionThe patients in our country more present as peripheralneuropathy, skin change and edema, whereas hepatomegaly, splenomegaly, erectile dysfunction, breast enlargement of males, amenorrheal, pleural effusion and ascites are next.
