Implication of Changes of Serum C-Reaction Protein and Matrix Metalloproteinase-9 in Patients with Acute Coronary Syndrome in Nursing
- VernacularTitle:急性冠脉综合征患者HS-CRP和MMP-9变化对临床护理的意义
- Author:
Yu-ling GAO
;
Li-xin JIA
;
Wei SHI
- Publication Type:Journal Article
- Keywords:
acute coronary syndrome (ACS), serum, high sensitive C-reaction protein (HS-CRP), matrix metalloproteinase-9 (MMP-9), nursing
- From:
Chinese Journal of Rehabilitation Theory and Practice
2006;12(6):480-481
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo explore the changes of serum high sensitive C-reaction protein (HS-CRP) and matrix metalloproteinase-9 (MMP-9) in patients with acute coronary syndrome (ACS) and their effects in nursing.Methods103 ACS patients, including 56 cases of unstable angina (UA)) and 47 cases of acute myocardial infarction (AMI), and other 40 persons (no abnormal results in coronary artery angiography, selected as control group) were examined for serum levels of HS-CRP and MMP-9. The difference among the groups was analyzed.ResultsThe HS-CRP levels of UA group, AMI group and control group were (3.87± 0.76 )g/L, (4.12 ±0.67)g/L and (1.67±0.38)g/L respectively; MMP-9 were (113.25±7.76)ng/ml, (193.09±25.87)ng/ml and (42.05±3.81)ng/ml respectively. The concentrations of HS-CRP and MMP-9 of ACS patients were significatly higher than those of the control group (P<0.01).ConclusionThe changes of HS-CRP and MMP-9 concentrations of ACS patients are remarkable, and may be as the markers to instruct nursing works.