Induction and Repair of bFGF and EGF Sponge to Endogenous Neural Stem Cells after Half Cut-off of Spine Cord in Rats
- VernacularTitle:大鼠脊髓损伤后bFGF、EGF海绵对内源性神经干细胞的诱导及修复作用
- Author:
Hai LIU
;
Tao HONG
;
Zhongcheng WANG
;
Yihua AN
;
Yong CUI
- Publication Type:Journal Article
- Keywords:
spinal cord injury, basic fibroblast growth factor (bFGF) and epidermal growth factor (EGF) sponge, endogenous neural stem cell, rat
- From:
Chinese Journal of Rehabilitation Theory and Practice
2007;13(6):501-503
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate induction and repair of basic fibroblast growth factor (bFGF) and epidermal growth factor (EGF) sponge to endogenous neural stem cells after acute spinal cord half cut-off in rats.MethodsThe differences of proliferation and differentiation of endogenous neural stem cells were compared between injured group and intervention treatment group.ResultsThere are remarkable differences between the injured group and intervention treatment group.ConclusionbFGF and EGF sponge can enhance the proliferation and differentiation of the neural stem cells in the test animal.