Results of determination of salidroside content in roots and rhizomes of cultivated and natural Rhodiola rosea L
- VernacularTitle:Тарималжуулсан болон зэрлэг алтангагнуур (Rhodiola rosea L)- ургамлын үндэс, үндэслэг ишэнд салидрозидын агууламжийг тодорхойлсон дүн
- Author:
Khishigjargal B
1
;
Lkhaasuren R
1
;
Batdorj D
1
;
Suvdaa T
2
;
Gantogtokh G
1
;
Orkhon N
1
;
Tsetsegmaa S
1
;
Khurelbaatar L
1
Author Information
1. Monos Group, Drug Research Institute
2. Monos Pharma Co., Ltd
- Publication Type:Journal Article
- Keywords:
Rhodiola rosea L;
general requirement for plant raw material;
salidroside
- From:Mongolian Medical Sciences
2021;195(1):51-55
- CountryMongolia
- Language:Mongolian
-
Abstract:
Introduction:Rhodiola rosea L. (R.rosea) is a popular plant in traditional medicine of the Nordic countries, Eastern
Europe, and Asia. R.rosea plants are successfully cultivated in Mongolia. The Botanical Garden of
Medicinal Plants under the “Monos” Group started to cultivate R. rosea since May 2015.
Objective:The aim of this research was to study the salidroside contents of R.rosea collected from Zavkhan
and Khuvsgul province, Mongolia, and cultivated in the Botanical Garden of Medicinal Plants, Drug
research Institute, Monos group.
Material and Methods:The underground parts of wild roseroot plants were collected from April to May 2020 from Jargalant
soum, Khuvsgul province, and Nomrog soum, Zavkhan province, 3-years and 4-years-old cultivated
R.rosea gathered from the Botanical Garden of Medicinal Plants in April 2020. For comparison,
4-year-old Rhodiola grenulata (R. grenulata) was ordered from Shanxi Zhendong Genuine Medicinal
Materials Development Co., Ltd, China, and used for the study. The quantity of the salidroside
constituents of the underground parts were compared and the sourcing of roseroot raw material was
evaluated. Chemical analysis of roots and rhizome of R. Rosea namely the appearance, identification,
moisture, organic impurities, mineral impurities, residue on ignition, water-soluble extractives, fresh
weight of roots, and salidroside content were determined according to the National Pharmacopoeia of
Mongolia (NPhM) 2011. Microbiological analysis was performed in accordance with the requirements
of grade 3b specified in Annex 1 of the Order No. A / 219 of the Minister of Health dated May 30,
2017 to determine the degree of microbiological purity in medicinal products of roots and rhizome
raw materials.
Result:The content of salidroside, the main biologically active substance of R.rosea plant, was 1.57% in
samples collected from Zavkhan province, 1.45% in samples collected from Khuvsgul province, 1.7%
in samples grown in China and 0.25% for 3-years-old samples and 1.89% for 4-years-old samples grown in the Botanical Garden of Medicinal Plants, Monos group, Mongolia. In addition, these raw
materials meet the general requirements for plant raw materials and microbiological parameters.
Conclusion:Samples of underground parts of R.rosea cultivated for 4 years in the Botanical Garden of Medicinal
Plants have the highest content (1.89%) of the salidrosde. Therefore, it is suggested that the roots
and rhizomes of R.rosea planted in the future can be standardized and used as a raw materials for
medicines.
- Full text:2021-195(1)-51-55.pdf
