Technological study to convert traditional powder medicine into modern dosage formulation
- VernacularTitle:Уламжлалт талх эмийг орчин үеийн эмийн хэлбэрт оруулах технологийн судалгаанаас
- Author:
Ganchimeg G
1
;
Lkhaasuren R
1
;
Odchimeg B
1
;
Badamtsetseg S
1
;
Sugarmaa B
1
;
Bayanmunkh A
1
;
Lkhagva L
1
;
Tsetsegmaa S
1
;
Khurelbaatar L
1
Author Information
1. Monos group, Drug Research Institute
- Publication Type:Journal Article
- Keywords:
Traditional powder medicine;
tablet form;
standardization
- From:Mongolian Medical Sciences
2021;195(1):38-42
- CountryMongolia
- Language:Mongolian
-
Abstract:
Introduction:The Mongolian people have been using traditional medicine for hundreds of years. However, there is
a need to produce traditional medicinal dosage forms such as capsules, tablets, decoctions easier to
drink, store and transport, and to standardize not only finished product, but the raw materials used for
traditional medicines in line with the current drug production, drug quality and safety requirements.
Therefore, in this study, we aim to standardize five ingredients of a traditional powder medicine,
which have been widely used for colds and flu in Mongolian, Chinese and Tibetan traditional medicine
practice, and to convert the powder drug into tablet form using qualified raw materials.
Materials and Methods:The study to convert multi-ingredient traditional powder into tablet was carried out at the Experimental
production pharmaceutical technology unit and Pharmaceutical chemistry Laboratory of the Drug
research institute, Monos Group, and the Quality control laboratory of medicine of Monos Pharm LLC.
Result:All raw materials were standardized and wet granulation method was used to prepare granules for
the tableting with qualified raw materials. 4 different models of the tablet form was prepared and
investigated. It was determined that model X-2 fully meets the general requirements for the tablet
form.
- Full text:2021-195(1)-38-42.pdf