Frequency of cerebral infarction and intra- and extracranial artery stenosis in Mongolian young adults
- VernacularTitle:Монгол залуу хүмүүст тохиолдох тархины шигдээс ба гавлын гаднах, доторх судасны нарийслын давтамж
- Author:
Delgermaa Ts
1
;
Baigalmaa G
1
;
Tsagaankhuu G
1
Author Information
1. Mongolian National University of Medical Sciences
- Publication Type:Journal Article
- Keywords:
Mongolian Young Adults;
Stroke;
Cerebral Ischemia;
Risk factors;
Carotid stenosis
- From:Mongolian Medical Sciences
2021;195(1):5-17
- CountryMongolia
- Language:Mongolian
-
Abstract:
Background:The frequency of cerebral infarction and stenosis of intra- and extracranial arteries may be vary with
age-group and gender.
Objective:This study was conducted to clarify the risk factors and characteristics of cerebral infarction and
stenosis of vessels in Mongolian young adults.
Methods:This was a prospective study, from October 2015 to July 2020, of 100 patients below 50 years
diagnosed with acute cerebral infarction. Patient characteristics were compared according to sex
(61 males and 39 females) and age group (29 patients were below 34 years and 71 patients were
35–49 years). Characteristics of acute cerebral infarction were studied by DWI-diffusion weighted
MRI imaging. Stenosis of intra- and extracranial arteries was diagnosed by duplex sonography, head
and cervical magnetic resonance angiography (MRA).
Results:Leading causes for cerebral infarction in the young patients were hypertension (71%), smoking
(57%), dyslipidemia (45%), diabetes (33%), and migraine with aura (25%). Lacunar Infarction was
most common in our patients (33%). Partial anterior circulation infarction was predominant in males
(45.9% vs 38.5%; P<0.05) and posterior circulation infarction in females (23.1% vs 11.5 %; P<0.05).
Small artery atherosclerosis was found in 33% cases, with higher prevalence in patients of the 35–49
years age-group. Intracranial stenosis was more common than extracranial stenosis, and middle
cerebral artery stenosis was most prevalent (38.9%). Stenosis in the anterior circulation was more
frequent than in the posterior circulation (P<0.001).
Conclusions:In these young patients, hypertension, smoking, dyslipidemia, diabetes, and migraine with aura were
common risk factors. Intracranial stenosis was most common, particularly in the middle cerebral
artery.
- Full text:2021-195(1)-5-17.pdf
