Effect of Neural Stem Cells Transplantation on Sequela after Traumatic Intracranial Hematoma
- VernacularTitle:神经干细胞移植治疗外伤性颅内血肿后遗症20例临床疗效分析
- Author:
Hongbin CHENG
;
Shaoshan HU
;
Yongri ZHENG
;
Min LI
;
Yihua AN
- Publication Type:Journal Article
- Keywords:
neural stem cell, trauma brain injury, Functional Independence Measure, brain hemorrhage
- From:
Chinese Journal of Rehabilitation Theory and Practice
2007;13(5):454-455
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the curative effect of neural stem cells (NSCs) transplantation on sequela after traumatic intracranial hematoma. Methods 20 patients with sequela after traumatic intracranial hematoma were treated with NSCs transplantation. Cells were engrafted into subarachnoid cavity via lumbar puncture. They were assessed with Functional Independence Measure (FIM) before and half a year after the transplantation. Results The FIM scores were significantly increased after the transplantation (P<0.01).Conclusion NSCs transplantation could promote functional recovery and improve the living quality of patients with sequela after traumatic intracranial hematoma in the aspects of self-care, sphincter control, mobility, locomotion, communication and social adjustment/cooperation.
