Clinical Significance of Measurment of D-Dimer and High Sensitive C-Reactive Protein in Serum for Acute Cerebral Infarction
- VernacularTitle:测定D-二聚体和超敏C-反应蛋白对急性脑梗死患者的临床意义
- Author:
Bing CHEN
;
Xianghong MENG
;
Xiaofei GENG
;
Wei WANG
;
Juan CHEN
;
Dongning WEI
- Publication Type:Journal Article
- Keywords:
cerebral infarction, D-Dimer, high sensitive C-reactive protein(Hs-CRP), National Institutes of Health Stroke Scale (NIHSS)
- From:
Chinese Journal of Rehabilitation Theory and Practice
2007;13(5):415-416
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the relationship of D-Dimer and high sensitive C-reactive protein in serum in acute cerebral infarction. Methods 64 patients with acute cerebral infarction were measured with the D-Dimer and Hs-CRP and compared with that of 50 healthy subjects as the controls. Their scores of National Institutes of Health Stroke Scale (NIHSS) were recorded and the correlation with the D-Dimer and Hs-CRP level was analyzed. Results Compared with those in controls, the levels of D-Dimer and Hs-CRP in patients with acute cerebral infarction were significantly higher (P<0.05), and those in patients with large infarction area were significantly higher than those in patients with small infarction area (P<0.01). The levels of D-Dimer and Hs-CRP uncorrelated with the scores of NIHSS.Conclusion The D-Dimer and Hs-CRP level is helpful to assess the acute cerebral infarction.