A Case of Carbamazepine-Induced Acute Interstitial Nephritis.
- Author:
Jong Hoon CHUNG
1
;
Young Kon KIM
;
Yong Eun KWON
Author Information
1. Department Internal Medicine, College of Medicine, Chosun University, Kwangju, Korea. jhchung@mail.chosun.ac.kr
- Publication Type:Case Report
- Keywords:
Acute interstitial nephritis;
Acute renal failure;
Carbamazepine
- MeSH:
Acute Kidney Injury;
Biopsy;
Carbamazepine;
Diagnosis;
Exanthema;
Fever;
Humans;
Nephritis;
Nephritis, Interstitial*;
Young Adult
- From:Korean Journal of Nephrology
2000;19(6):1183-1186
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Acute interstitial nephritis is a disorder that primarily affect the renal tubule and interstitium. This disease may result from a variety of cause but drug have emerged as the most common cause of acute interstitial nephritis. Characteristically, in acute interstitial nephritis mononuclear cell infiltrate the interstitium, particularly in cortex. Diagnosis of acute intersitital nephritis can be made from historical information, physical examination,or laboratory test. But renal biopsy is the most definitive method of diagnosis. Carbamazepine has been used as a drug for treatment of convulsive disorder. This drug cause rarely renal problem. The authors experienced a case of carbamazepine induced acute interstitial nephritis in a 20 years old man who showed skin rash and mild fever, deminished renal function, and who was diagnosed by history,physical examination, renal biopsy.
