Results of normal microflora of the skin of the population covered by the study of immunosuppression and risk factors for injectable infectious diseases
- VernacularTitle:Тарилгатай халдварт өвчний дархлал тогтоц ба түүнд нөлөөлөх эрсдэлт хүчин зүйлсийн судалгаанд хамрагдсан хүн амын арьсны хэвийн микрофлор
- Author:
Budkhand O
1
;
Ichihkhoroloo B
1
;
Ankhmaa B
1
;
Ariuntugs S
1
;
Nomin-Erdene B
1
;
Khaliun T
1
;
Gansmaa M
1
;
Baigali B
2
;
Altanchimeg S
2
;
Dashpagma O
2
;
Oyunbileg J
1
Author Information
1. National center for public health, Department of biotechnology and innovation
2. National center for infectious disease, Department of immunization
- Publication Type:Journal Article
- Keywords:
normal microflora;
specific immunity;
fungus;
microorganism
- From:Mongolian Medical Sciences
2021;196(2):75-83
- CountryMongolia
- Language:Mongolian
-
Abstract:
Introduction:Researchers have found that people living in polluted areas have a lower ability to resist skin bacteria
and increase the number of skin microflora. Decreased immune function increases the risk of sore
throat, influenza, respiratory infections, pneumonia and gastrointestinal diseases. One of the main
indicators of the human immune system is the normal microflora.
Goal:To study the relationship between normal human microflora and specific immunity.
Material and Methods:This study was conducted within the framework of the project “Effects of non-specific immune factors
on injectable infectious disease immune system”. The survey sampled 10 households from Dornod
aimag, 8th khoroo of Chingeltei district, Ulaanbaatar city, and 3rd khoroo of Baganuur district. A
total of 176 people aged 6 months to 50 years were involved. A total of 528 swab samples and 31
blood samples were collected from the throat, tonsils, skin and mucous membranes to study the
relationship between normal human microflora and specific immunity.
The research methodology was discussed at the meeting of the Academic Council of the Ministry of
Social Welfare and the Medical Ethics Review Committee under the Ministry of Health (January 5,
2018, Resolution 646) and the research was approved.
Results:The total number of normal microorganisms in the skin and mucous membranes of the study
participants changed, and the number of hemolytic strains and fungi increased. 58%-67% of the
participants had normal and long-term immunity against diphtheria and tetanus, while 5% -14% were
not. This result was as high as in urban and rural areas.
Conclusion:This result was as high as in urban and rural areas. As the age group increases, the level of the
body’s specific immunity decreases, the structure of the normal microflora changes, and the number
of fungi and hemolytic bacteria increases. Furthermore, it is necessary to study specific and nonspecific immunity in detail in relation to environmental pollution indicators.
- Full text:2021-196(2)-75-83.pdf
