Effect and Safety of Intravenous Sodium Valproate in Treatment of Pediatric Patients with Status Epilepticus
- VernacularTitle:丙戊酸静脉制剂治疗儿童癫痫持续状态的疗效及安全性
- Author:
Jin DAI
;
Jian-ning MAI
;
Xiu-ying WANG
- Publication Type:Journal Article
- Keywords:
children, intravenous sodium valproate, status epilepticus
- From:
Chinese Journal of Rehabilitation Theory and Practice
2006;12(4):345-346
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo explore the effect and safety of intravenous sodium valproate in treatment of pediatric patients with status epilepticus (SE).MethodsTwenty-five children suffering from convulsive SE were treated with intravenous sodium valproate after failure of the conventional treatment, in a dose of tolerability 15 mg/kg and 1～2 mg/kg daily.ResultsIn 25 cases, there were 23 cases (92%) with ≥50% seizure reduction and 11 cases (44%) with complete cessation. Except for winking in 7 cases (28%), no other adverse effects had been found.ConclusionIntravenous sodium valproate is effective and safe on pediatric patients with SE who are resistant to conventional drugs.
