Prevalence of hypoglycemia among type 2 diabetics undergoing hemodialysis in a university hospital
10.35460/2546-1621.2018-0057
- Author:
Maria Concepcion H GUNGON
1
;
Elaine C CUNANAN
1
Author Information
1. Section of Endocrinology, Diabetes and Metabolism, Department of Internal Medicine, University of Santo Tomas Hospital, Manila, Philippines
- Publication Type:Journal Article
- Keywords:
Diabetes;
CKD
- MeSH:
Renal Dialysis;
Hypoglycemia;
Kidney Failure, Chronic
- From:
Journal of Medicine University of Santo Tomas
2020;4(2):510-517
- CountryPhilippines
- Language:English
-
Abstract:
Background:The overall increase in the number of
people with diabetes mellitus has a major impact on
the increasing number of patients with diabetic kidney
disease (DKD). Hypoglycemia that is brought about
by altered glucose homeostasis and the hemodialysis
process in patients with DKD poses a great challenge
to clinicians in achieving blood glucose control. This
study has been undertaken to evaluate the prevalence
of hypoglycemia among diabetics undergoing hemodialysis and determine the clinical factors predicting
the development of hypoglycemia.
Methods:We conducted a prospective, cross-sectional study that included 75 patients with diabetes
mellitus undergoing maintenance hemodialysis at the
University of Santo Tomas Hospital, Center for Kidney
Disease. The patients’ predialysis and hourly intradialytic serum glucose levels were measured until the
end of the session. Hypoglycemia was considered as
a blood glucose ≤70 mg/dL with/without symptoms.
Results:Elderly patients and in-hospital patients
tend to develop hypoglycemia with a p-value of
0.0028 and 0.001, respectively. Old age (p-value
0.0093), female sex (p-value 0.0224), hypertension
(p-value 0.0301), CAD (p-value 0.0058), frequency of hemodialysis (p-value 0.0000), no caloric intake
during the dialysis session (p-value 0.0022) and admission (p-value 0.0007) predicted hypoglycemia in
our study
Conclusions:In conclusion, the prevalence of hypoglycemia among patients with type 2 diabetes mellitus
undergoing maintenance hemodialysis in our setting
is 12%. There is an increased rate of hypoglycemia
amongst the elderly as well as admitted patients. Our
results identifi ed old age, presence of CAD, increased
frequency of hemodialysis and hospital admission as
the predictors of hypoglycemia.
- Full text:1 JMUST 037.pdf
