Preliminary study of fogging process for fixing high-concentration radioactive aerosol 131I contamination in a radiopharmaceutica production unit
10.13491/j.issn.1004-714X.2021.02.009
- VernacularTitle:放射性药品生产单位雾化固定高浓度131I放射性气溶胶的初步研究
- Author:
Shuai GAO
1
;
Haitao QIAO
1
;
Jing ZHANG
1
;
Pei HU
1
;
Hongpeng SHUAI
1
;
Huilong YIN
1
;
Bingwen MA
1
Author Information
1. HTA Co., Ltd., Beijing 102413 China.
- Publication Type:RadiationMonitoring/OriginalArticles
- Keywords:
Fogging and Fixing Process;
High-Concentration;
Aerosol 131I Contamination;
Radiopharmaceutical Producing
- From:
Chinese Journal of Radiological Health
2021;30(2):165-167
- CountryChina
- Language:Chinese
-
Abstract:
Objective To prove the feasibility of a Fogging Process in fixing high-concentration radioactive aerosol 131I contamination. Methods High-concentration radioactive aerosol 131I contamination in an 131I-operating glovebox for radiopharmaceutical production was disposed by using fogging and fixing process. The aerosol 131I concentrations were detected and the results were analyzed. Results After a 120 minutes fixing, the 131I contamination in this glovebox reduced from(289 ± 9) DAC and (304 ± 6) DAC to (21.7 ± 2.0) DAC and (26.2 ± 1.8) DAC. After a 180 minutes fixing, the 131I contamination in this glovebox reduced from (259 ± 10) DAC to (1.80 ± 0.18) DAC. These results showed that no aerosol 131I contamination was raised again after 24-hours finishing this task. Conclusion Aerosol 131I concentration in a limited space could be controlled by using a fogging and fixing process, which could reduce the risk of internal exposure of staff. This process could be used by radiopharmaceutical production as an emergency management for dispose high-concentration radioactive aerosol 131I contamination.