Effect of Simvastatin on Severe Complications of Subarachnoid Heamorrhage
- VernacularTitle:辛伐他汀对蛛网膜下腔出血严重并发症的影响
- Author:
Shi-wen WU
;
Wei-ya MA
;
Hong BIAN
;
Guang YANG
;
Wenbin ZHANG
- Publication Type:Journal Article
- Keywords:
simvastatin, subarachnoid heamorrhage, cerebral vasospasm, hydrocephalus
- From:
Chinese Journal of Rehabilitation Theory and Practice
2006;12(4):326-328
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo investigate the effect of simvastatin on severe complications and prognosis of subarachnoid heamorrhage (SAH).Methods98 cases with SAH were randomly divided into the treatment groups and control group (finally, there were 32 cases in treatment group, 48 cases in control group). Patients in treatment group were given simvastatin 20 mg/day, and those in control group were treated with routine therapy. The incidences of cerebral vasospasm, hydrocephalus, rebleeding and mortality between the two groups were compared.ResultsThe incidence of hydrocephalus of treatment group was 3.13%; that of control group was 18.7%, there was a significantly difference between two groups (P<0.05). There were no significant differences for incidences of cerebral vasospasm, rebleeding and mortality between two groups (P>0.05).ConclusionSimvastatin can reduce the occurrence of hydrocephalus after SAH.
