Empirical Study of Sedative Effect of TL-Ⅰ Prescription in Rat
- VernacularTitle:TL-Ⅰ号方镇静作用的实验研究
- Author:
Yong-lie ZHAO
;
Yu-lai WANG
;
Ying GAO
;
Ziwang LIU
;
Aicheng WANG
- Publication Type:Journal Article
- Keywords:
sedation, mouse tail suspension test, analytical system of animal behavior-spontaneous movement, TL-Ⅰ prescription
- From:
Chinese Journal of Rehabilitation Theory and Practice
2006;12(4):309-310
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo investigate the sedative effect of TL-Ⅰ prescription.Methods72 healthy ICR mice were randomly divided into 6 groups: normal group, model group, positive control group, large doses Chinese materia medica group, middle doses Chinese materia medica group and small doses Chinese materia medica group. The active behavior of migraine-model-mouse was detected with tail suspension test and the analytical system of animal behavior-spontaneous movement.ResultsTL-Ⅰ prescription could prolong the quiescent time of migraine-model-mouse and shorten the active journey and time in the autonomic active box of migraine-model-mouse.ConclusionTL-Ⅰ prescription has sedative effect.