Research progress on effect and mechanism of diesel exhaust particles on asthma

VernacularTitle:柴油机尾气颗粒对哮喘的作用及其机制的研究进展
Author: Chaohui MU ¹ ; Qinghai LI ¹ ; Xinjuan YU ¹ ; Yize YIN ² ; Wei HAN ^{2
,

3}
Author Information

1. Department of Respiratory and Critical Care Medicine, Qingdao University Affiliated Qingdao Municipal Hospital, Qingdao, Shandong 266071, China.
2. School of Public Health, Qingdao University, Qingdao, Shandong 266071, China.
3. Department of Respiratory and Critical Care Medicine, Qingdao University Affiliated Qingdao Municipal Hospital, Qingdao, Shandong 266071, China
Publication Type:Specialcolumn:Healthhazardsofdieselexhaustexposure
Keywords: diesel exhaust particle; bronchial asthma; oxidative stress; airway inflammation; airway remodeling
From: Journal of Environmental and Occupational Medicine 2023;40(5):524-528
CountryChina
Language:Chinese
Abstract: As a source of traffic-related air pollution, diesel particulate matter (DPM) associate with a variety of lung-related diseases, but there is no systematic review of the relationship between DPM and the development and progression of asthma. This article reviewed the relationship between DPM and asthma, the effect and mechanism of DPM on airway inflammation and remodeling in asthma, and illustrated that DPM exposure may participate in airway inflammation and remodeling through oxidative stress, immune regulation and regulation of lung and intestinal microecology, so as to promote the development and progression of asthma.