Effect of L-carnitine on Patients with Microvascular Angina
- VernacularTitle:左卡尼汀治疗微血管性心绞痛疗效观察
- Author:
Yueyan LI
;
Zhihua QUAN
;
Xiaojin TAN
;
Zhicheng YANG
- Publication Type:Journal Article
- Keywords:
L-carnitine, microvascular angina, myocardial ischemia, exercise tolerance
- From:
Chinese Journal of Rehabilitation Theory and Practice
2007;13(2):171-172
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo observe the therapeutic efficacy of L-carnitine on patients with microvascular angina (MVA).Methods48 MVA patients were divided randomly into the trail group and control group with 24 cases in each group. The patients of the trail group were treated with L-carnitine vein dropping, those of the control group took isosorbide-mononitrate orally. All treatment lasted for 12 weeks.ResultsAfter the treatment, attack times of MVA and consumption of nitroglycerin of the patients in two groups decreased obviously ( P<0.01). The time for inducing angina, the time for 0.1 mV ST segment depression, the total exercise time and ∑ST depression by exercise were improved obviously ( P<0.05). The serum total cholesterol, triglyceride and low density lipoprotein cholesterol decreased by 20.3%, 32.7% and 16.6% respectively, and high density lipoprotein cholesterol levels increased by 34.5% in the trail group ( P<0.01).ConclusionL-carnitine has affirmative effect on MVA, same as isosorbide-mononitrate.
