Effects of bone marrow stromal cells on endothelial cells proliferation and microvessel formation in vitro
- VernacularTitle:骨髓基质细胞对血管内皮细胞生长及微血管形成的影响
- Author:
Peng-fei ZHANG
;
Ya-zhuo ZHANG
;
Qing-guo LI
;
Meizhen SUN
;
Hongyun WANG
;
Le HE
- Publication Type:Journal Article
- Keywords:
bone marrow stromal cells, endothelial cells, microvessel
- From:
Chinese Journal of Rehabilitation Theory and Practice
2006;12(1):14-15
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo observe the effects of bone marrow stromal cells (BMSCs) on vessel endothelial cells proliferation and microvessel formation in vitro.MethodsBMSCs and brain vessel endothelial cells were separated from adult and divided into co-culture group of BMSCs and endothelial cells, medium group of BMSCs, comparison group. Endothelial cells proliferation and microvessel formation were observed. ResultsEndothelial cells were promoted to proliferate and formate the microvessel in medium group and co-culture group. And the effect was prominence in co-culture group.ConclusionBMSCs can promote the proliferation and microvessel formation of endothelial cells.