Dosimetry of organs at risk between involved field radiation and extended field radiation in patients with thoracic esophageal cancer
10.13491/j.issn.1004-714X.2022.02.014
- VernacularTitle:胸段食管癌累及野放疗与扩大野放疗对危及器官的辐射剂量学分析
- Author:
Cheng YUAN
1
;
Mingrui LIU
2
;
Linxin SHI
1
;
Weixian SHAO
1
;
Qiang WANG
1
;
Aonan DU
1
;
Wen ZHANG
1
;
Jianwei SUN
1
;
Hui MIAO
1
Author Information
1. Xuzhou Cancer Hospital, Xuzhou 221005 China.
2. Medical College of Nantong University, Nantong 226001 China.
- Publication Type:OriginalArticles
- Keywords:
Thoracic esophageal cancer;
Intensity modulated radiotherapy;
Involved field radiation;
Extended field radiation;
Organs at risk
- From:
Chinese Journal of Radiological Health
2022;31(2):210-213
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the irradiation dose of organs at risk (OAR) in involved field radiation and extended field radiation in patients with thoracic esophageal cancer who received intensity modulated radiotherapy (IMRT). Methods A total of 40 patients with thoracic esophageal cancer were treated with IMRT. The involved field, extended field, and OAR were outlined to generate IMRT plans. The conformity index (CI) and homogeneity index (HI) of planning target volume (PTV) and the irradiation parameters of OAR were evaluated for the two plans. Paired t-test was used for comparison of irradiation parameters. Results The PTV of both plans received the prescribed dose. There were no significant differences in CI and HI of PTV between the two groups (P = 0.317, 0.130). There were significant differences in average lung dose, lung V5, lung V20, lung V30, spinal cord Dmean, heart Dmean, heart Dmax, heart V30, heart V40, and heart V60 between the two groups (P < 0.01). Conclusion Compared with the extended field, the involved field can reduce the irradiation dose of ORA in patients with thoracic esophageal cancer, thus reducing the risk of radiation.