Research progress of Coxsackievirus A21
10.3969/j.issn.1006-2483.2023.03.026
- VernacularTitle:柯萨奇病毒A21型研究进展
- Author:
Jie YAN
1
,
2
;
Qunhua BAI
2
;
Hua ZHAO
1
;
Hua LING
1
;
Jingyao PENG
1
Author Information
1. Chongqing Municipal Key Laboratory for High Pathogenic Microbes , Chongqing Center for Disease Control and Prevention , Chongqing 400042 ,China
2. School of Public Health , ChongQing Medical University , Chongqing 400016 , China
- Publication Type:Journal Article
- Keywords:
Coxsackievirus A21;
Epidemiology;
Oncolysis
- From:
Journal of Public Health and Preventive Medicine
2023;34(3):119-123
- CountryChina
- Language:Chinese
-
Abstract:
Enteroviruses are currently divided into groups A to J, among which groups A to D can infect human body. People infected with enterovirus can present invisible infection, which can lead to different clinical symptoms when the immunity is weakened. Among the diseases caused by enteroviruses, hand-foot-mouth disease, herpetic angina, and encephalitis have attracted much attention. Coxsackie virus A21 (CV-A21) belongs to enterovirus C group, which mainly causes acute respiratory tract infection. According to research reports, CV-A21 infection has been found in many countries and regions, and the infection scope is gradually expanding. In the past two years, it has been found that CV-A21 infection has a significant association with the outbreak of acute respiratory tract infection. This indicates that acute respiratory tract infection caused by CV-A21 infection may have potential public health problems. However, there are few studies on the epidemiology and pathogenic mechanism of this virus, and most of the studies are on the mechanism of its oncolytic action on specific malignant tumors. Therefore, in this paper, the structural characteristics, epidemiological characteristics, infection mechanism and oncolytic effects of CV-A21 are reviewed to provide relevant clues for the understanding and exploration of CV-A21.
