Case-control study of risk factors for autoimmune thyroiditis in adults in the Xindu region
10.3969/j.issn.1006-2483.2023.03.017
- VernacularTitle:成都新都区成人自身免疫性甲状腺炎危险因素的病例对照研究
- Author:
Yang LIU
1
;
Quanmin CHEN
1
;
Erqun WANG
2
Author Information
1. Chengdu Xindu District Hospital of Traditional Chinese Medicine , Chengdu Second Hospital of Traditional Chinese Medicine , Chengdu , Sichuan 610500 , China
2. Xindu District Center for Disease Control and Prevention , Chengdu , Sichuan 610500 , China
- Publication Type:Journal Article
- Keywords:
Adult;
Autoimmune thyroiditis;
Case control
- From:
Journal of Public Health and Preventive Medicine
2023;34(3):79-82
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the influencing factors of autoimmune thyroid disease in Xindu region and provide a basis for preventing the occurrence of autoimmune thyroiditis.Methods Using case-control study, 581 autoimmune thyroid patients treated in 2016-2020 in Chengdu Xindu District Hospital of 2020, and 450 healthy patients were selected as the control group. Relevant data were obtained and the influencing factors of adult autoimmune thyroid disease were analyzed by univariate and multivariate logistic regression model. Results Univariate results showed that the observed BMI of 30.0 kg/m2, hyperlipidemia, metabolic syndrome and urinary iodine (<100 μg/L and> 200 μg/L) were higher than control group, with thyroid function [free triiodinated thyrigenine (FT3), free thyroxine (FT4) and thyroid stimulating hormone (TSH)), autothyroid antibody [thyroglobulin antibody (TGAb), antithyroid peroxidase antibody (TPOAb),] greater than control group (P <0.05).According to logistic regression analysis, body mass index 30.0, TGAb positive, TPOAb positive, hyperlipidemia, and metabolic syndrome were independent risk factors for adult autoimmune thyroiditis [OR (95% CI): 1.965 (1.340), 3.1262 (1.568-8.243), 3.089 (1.753-7.166), 2.507 (1.164 -4.956), 2.218 (1.207 -3.362), P <0.05]. Conclusion Body mass index of 30.0 kg/m2, hyperlipidemia and metabolic syndrome are the risk factors for adult autoimmune thyroiditis in Xindu region.Controlling weight, controlling autoimmune thyroiditis and metabolic syndrome are the key to reducing adult autoimmune thyroiditis in Xindu region.
