Investigation of viral etiology with sever acute respiratory infection of hospitalized patients in Guangdong Province from 2019 to 2021
10.3969/j.issn.1006-2483.2023.03.008
- VernacularTitle:2019—2021年广东省住院严重急性呼吸道感染病毒病原谱分析
- Author:
Jiamin XIE
1
,
2
,
3
;
Yunqiang ZHANG
1
;
Kang YANG
2
,
3
,
4
;
Xinxin HUANG
1
,
2
,
3
;
Huishi DENG
2
,
3
,
5
;
Jie WU
1
,
2
,
3
;
Lirong ZHOU
2
,
3
Author Information
1. School of Public Health , Southern Medical University , Guangzhou , Guangdong 510000, China
2. Guangdong Province Centers for Disease Control Prevention , Guangzhou , Guangdong 510000 , China
3. Guangdong Workstation for Emerging Infectious Disease Control and Prevention , Chinese Academy of Medical Sciences , Guangzhou , Guangdong 510000 , China
4. School of Public Health , Sun Yat-Sen University ,Guangzhou , Guangdong 510000 , China
5. Department of Public Health and Preventive Medicine, School of Medicine, Jinan University, Guangzhou 510000 , Guangdong China
- Publication Type:Journal Article
- Keywords:
Severe acute respiratory infection;
Respiratory viruses;
Pathogenic spectrum;
Hospitalized cases
- From:
Journal of Public Health and Preventive Medicine
2023;34(3):38-42
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the infection status and epidemiological characteristics of viral pathogens in hospitalized patients with severe acute respiratory infection (SARI) in Guangdong Province from 2019 to 2021, so as to provide reference for clinical diagnosis and prevention. Methods The respiratory tract samples of SARI patients collected from 2019 to 2021 were detected and analyzed for respiratory syncytial virus (RSV), adenovirus (ADV), human rhinovirus/enterovirus (HRV/EV), human metapneumonic virus (HMPV) and other common respiratory viruses using Luminex respiratory multi-pathogen detection technology. Results A total of 1 948 influenza-negative cases were collected, of which 24.28 % were positive detection of virus infection. HRV/EV was the highest (10.32%), followed by RSV (4.31%). The detection rates were statistically significantly different among different age groups (χ2=176.186，P<0.05), and the highest detection rate was found in the group aged at 0 to 4 years (41.50%). There was no statistically significant between the male virus detection rate and the female virus detection rate (χ2=0.042，P>0.05). The detection peaks of RSV were mainly concentrated in summer and autumn, while HMPV was prevalent in winter, and HRV/EV and ADV had no obvious seasonality. Mixed infection was found in 39 samples, and the mixed infection rate was 2.00%. In the mixed infection cases, HPIV and HRV/EV combined infection was the most common. Conclusion HRV/EV, RSV, HMPV and ADV are predominant viral pathogens in SARI influenza-negative hospitalized cases in Guangdong Province from 2019 to 2021. It is recommended to strengthen the surveillance of SARI cases in children under 5 years old.
