Characteristics and Mechanism of Brain Default Mode Network Dysfunction in Primary Insomnia
10.13471/j.cnki.j.sun.yat-sen.univ（med.sci）.2023.0322
- VernacularTitle:原发性失眠大脑默认网络功能损害的特点及其机制
- Author:
Jing-yi YANG
1
;
Jun-zhang TIAN
1
Author Information
1. Department of Radiology， Guangdong Second Provincial General Hospital， School of Medicine， Jinan Unniversity， Guangzhou， 510317， China
- Publication Type:Review
- Keywords:
primary insomnia;
default mode network;
dysfunction;
neuroimaging
- From:
Journal of Sun Yat-sen University(Medical Sciences)
2023;44(3):528-533
- CountryChina
- Language:Chinese
-
Abstract:
Primary insomnia is one of the common sleep disorders. It is a type of insomnia with unknown causes， which is often accompanied by a variety of daytime dysfunction and sleep-wake disorders. Neuroimaging and neuroelectrophysiology studies suggest that there may be default mode network dysfunction in patients with primary insomnia， which is closely related to daytime dysfunction and sleep-wake disorder. This article summarizes the characteristics of default mode network dysfunction of primary insomnia and introduces related research in neural structural imaging， functional imaging and neuroelectrophysiology， as well as the role and the mechanism of default mode network impairment leading to daytime dysfunction and sleep-wake disorder of primary insomnia.
