Effect of Low-dose Reboxitine on Post-schizophrenic Depression:30 Cases Report
- VernacularTitle:小剂量瑞波西汀治疗精神分裂症后抑郁30例
- Author:
Wei JI
;
Chuancai HE
;
Hongbo PENG
- Publication Type:Journal Article
- Keywords:
schizophrenia, post-schizophrenic depression, reboxitine, treatment
- From:
Chinese Journal of Rehabilitation Theory and Practice
2007;13(1):90-91
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo explore the efficacy and side-effects of reboxitine on post-schizophrenic depression.Methods30 patients with post-schizophrenic depression according CCMD-Ⅲ accepted reboxitine 4～8 mg/d in addition to antipsychotic drugs for 6 weeks. Efficacy and side-effects were determined with Hamilton Depression Scale (HAMD), Brief Psychiatric Rating Scale (BPRS), Scale for Assessment of Negative Symptoms (SANS), Treatment Emergent Symptom Scale (TESS) before and 2, 4, 6 weeks after treatment. ResultsThe score of HAMD were obviously improved after the treatment(P<0.01), as well as that of negative psychotic symptoms in BPRS and TESS. Slight symptoms that may be associated to the Reboxitine were obvioused seldom, and all recovered without any treating. ConclusionLow-dose rebositine is effective on post-schizophrenic depression with few side-effects and good compliance.
