Effect of Recombinant Tissue-type Plasminogen Activator on Hyperacute Cerebral Infarction
- VernacularTitle:超早期重组组织型纤溶酶原激活物溶栓治疗脑梗死的临床研究
- Author:
Zhaohui LI
- Publication Type:Journal Article
- Keywords:
recombinant tissue-type plasminogen activator (rt-PA), vein thrombolysis, cerebral infarction
- From:
Chinese Journal of Rehabilitation Theory and Practice
2007;13(1):72-73
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo study the efficacy and safety of intravenous recombinant tissue-type plasminogen activator (rt-PA) on hyperacute cerebral infarction. Methods41 patients with the supra-early acute cerebral infarction were divided into two groups: thrombolytic group (n=21) and control group (n=20). They were evaluated with European Stroke Scale (ESS) and Barthel Index before and 24 h, 21 d, 90 d after treatment. ResultsThe scores of the thrombolytic group showed more efficacious than that of the control groups (P<0.05). One patient suffered from cerebral hemorrhage in thrombolytic group, however his prognosis was good. There was no death in both groups. ConclusionThrombolytic therapy with rt-PA in the hyperacute cerebral infarction shows positive effect and safety.
