Significance of evaluation of D-dimer in COVID-19 patient: Case report
- VernacularTitle:КОВИД-19 халдвартай өвчтөнд Д димер үзүүлэлтийг үнэлэхийн ач холбогдол: Тохиолдлын судалгаа
- Author:
Bayarjavkhlan Ch
1
;
Battulga Ch
2
;
Buyanjargal E
2
;
Byambalkham B
2
;
Jargal-Erdene B
1
;
Naranmandakh D
3
;
Munkhsaikhan B
2
;
Munkhbat T
3
;
Oyungerel S
1
;
Enkhnomin O
1
;
Gantuya L
2
;
Ulziitsetseg Ts
1
Author Information
1. Department of Laboratory Medicine, Gurvangal general hospital
2. Department of Diagnostics, Gurvangal general hospital
3. Department of Internal Medicine, Gurvangal general hospital
- Publication Type:Journal Article
- From:
Health Laboratory
2021;14(2):23-32
- CountryMongolia
- Language:Mongolian
-
Abstract:
Introduction:Coronavirus infection 2019 (Ковид-19) is an infection caused by a novel virus and induces severe ARDS. КОВИД-19 pandemic has rapidly spreaded in 221 countries, 245,373,039 cases and 4,979,421 mortalities have been reported. Pulmonary and renal thrombotic angiopathy occur in patients with complications of ARDS, sepsis, and multi-organ failure. Elevated D-dimer in КОВИД-19 patients has been reported firstly by doctors in Wuhan, China. In addition, many studies have revealed that elevated D-dimer has been associated with the severity of the diseases, an increased rate of poor prognosis.
Objective:We aim to determine D-dimer in КОВИД-19 patients, and patient condition a decrease of D-dimer level after administration of anticoagulant therapy.
Case report:We introduce a rare case of КОВИД-19. Laboratory test results and the effect of anticoagulant therapy have been evaluated during the infection. 85 aged women were admitted with a diagnosis other than КОВИД-19. PCR for SARS-Cov-2 was negative on the previous day of admission, and Sars-Cov-2 Ag rapid test was also negative on the admission day. However, the D-dimer test result was much higher with 7120 ng/мл and X-ray and CT revealed a similar pattern to the КОВИД-19 patient. Then anti-Sars-Cov-2 test was positive with 4,08 COI. Based on laboratory test results of D-dimer, LDH, CRP, and CT pattern the patient was diagnosed with post-КОВИД-19 pneumonia, and anticoagulant therapy was initiated additionally to prevent hypercoagulation induced by КОВИД-19. D-dimer test taken before administration of anticoagulant therapy increased more to 10910 ng/мл. 3 days later D-dimer level decreased to 8180ng/мл and the patient’s condition was improved.
Conclusion:The evaluation of D-dimer of the patients with КОВИД-19 is highly significant. Anticoagulant therapy might be necessary for КОВИД-19 patients with high D-dimer level in serum. Further studies are needed to assess the long-term outcome of the illness and mortality.
- Full text:HL-2021-14(2)-23-32.pdf
