Bcl-2/Bax and Spinal Cord Injury(review)
- VernacularTitle:Bcl-2/Bax与脊髓损伤
- Author:
Liubo XIONG
;
Zheng YANG
;
Yan XU
;
Xiao ZHANG
- Publication Type:Journal Article
- Keywords:
spinal cord injury, Bax, Bcl-2, medicine, transgenic, neurenergen
- From:
Chinese Journal of Rehabilitation Theory and Practice
2009;15(12):1147-1149
- CountryChina
- Language:Chinese
-
Abstract:
Apoptosis play an important role in the process of secondary spinal cord injury(SCI). Bcl-2 is a multigene family, which have fifteen members. Bcl-2 and Bcl-xL can inhibit apoptosis, but Bax, Bad, Bak, and Bcl-xS can promote apoptosis. Bcl-2 and Bax is the most representative gene in Bcl-2 gene family, Bcl-2/Bax determine cells whether goes to die. In this paper, we reviewed the latest developments in Bcl-2/Bax adjustment for SCI.
