Mechanism of antagonistic effects of Andrographis paniculata methanolic extract against Staphylococcus aureus
10.1016/j.apjtm.2017.07.009
- Author:
Roslinah Mohamad HUSSAIN
1
;
Zayan Nabilah Rasyidah Abd. RAZAK
1
;
Wan Mazlina Md SAAD
1
;
Maimunah MUSTAKIM
1
Author Information
1. Department of Medical Laboratory Technology, Faculty of Health Sciences, Universiti Teknologi MARA (UiTM)
- Publication Type:Journal Article
- Keywords:
Andrographis paniculata;
Antagonistic effects;
Catalase;
Oxidative stress resistance;
Staphylococcus aureus;
Superoxide dismutase
- From:
Asian Pacific Journal of Tropical Medicine
2017;10(7):685-695
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effects of Andrographis paniculata (Burm.f.) Wall. Ex Nees (A. paniculata) on expressions and activities of catalase, superoxide dismutase and alkylhydroperoxide reductase C in Staphylococcus aureus (S. aureus) with respect to its survival in vitro. Methods Antioxidative property of methanolic leaves extract of A. paniculata (0.06 mg/mL). Minimum inhibitory concentration (MIC) was determined by its ability to reduce hydrogen peroxide (H
