Evaluating the effect of Myrtus communis on programmed cell death in hydatid cyst protoscolices
10.1016/j.apjtm.2017.10.010
- Author:
Mojtaba SHAHNAZI
1
;
Moazzam Dosti JONDABEH
1
;
Hamidreza AGHAEI
1
;
Mehrzad SARAEI
1
;
Mojtaba SHAHNAZI
2
;
Abbas AZADMEHR
3
;
Abbas AZADMEHR
4
;
Reza HAJIAGHAEE
5
;
Reza NORIAN
6
;
Mahmood ALIPOUR
7
Author Information
1. Department of Parasitology, Qazvin University of Medical Sciences
2. Cellular & Molecular Research Institute, Qazvin University of Medical Sciences
3. Department of Immunology, Qazvin University of Medical Sciences
4. Department of Immunology, Babol University of Medical Sciences
5. Medicinal Plants Research Center, Institute of Medicinal Plants, ACECR
6. Department of Microbiology, Faculty of Veterinary Medicine, Urmia University
7. Department of Social Medicine, Qazvin University of Medical Sciences
- Publication Type:Journal Article
- Keywords:
Caspase;
Echinococcus granulosus;
Myrtus communis;
Programmed cell death;
Protoscolex
- From:
Asian Pacific Journal of Tropical Medicine
2017;10(11):1072-1076
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the possible involvement of programmed cell death strategy in hydatid cyst protoscolices following treatment with Myrtus communis (M. communis) as an herbal medicine. Methods Protoscolices were aseptically collected from sheep liver hydatid cysts. Evaluating the effect of M. communis extract on programmed cell death and increased activity of caspases 3, 8, and 9 in hydatid cyst protoscolices was conducted by treating the protoscolices with different concentration (5, 50, and 100 mg/mL) of M. communis extract at 37 °C and 5% CO
