Pharmacological basis for the medicinal use of Michelia champaca in gut, airways and cardiovascular disorders

Author: Fatima SAQIB ¹ ; Zubia MUSHTAQ ¹ ; Khalid JANBAZ ¹ ; Imran IMRAN ¹ ; Saikat DEAWNJEE ² ; Muhammad ZIA-UL-HAQ ³ ; Lorena DIMA ⁴
Author Information

1. Faculty of Pharmacy, Bahauddin Zakariya University
2. Advanced Pharmacognosy Research Laboratory, Department of Pharmaceutical Technology, Jadavpur University
3. Office of Research, Innovation and Commercialization, Lahore College for Women University
4. Faculty of Medicine, Transilvania University of Brasov
Publication Type:Journal Article
Keywords: Airway relaxant; Ca; Michelia chamapaca; Spasmolytic; Vasodilator
From: Asian Pacific Journal of Tropical Medicine 2018;11(4):292-296
CountryChina
Language:Chinese
Abstract: Objective: To discover the mechanism behind ameliorative effects of Michelia champaca (M. champaca) in gastrointestinal, respiratory and cardiovascular disorders. Methods: Anti- spasmodic potential was evaluated by trying the M. champaca extract (aqueous:ethanolic) on rabbit aorta, trachea and jejunum in vitro. Isotonic and isometric transducers coupled with Power Lab data acquisition system was used to record the responses of isolated tissues. Results: M. champaca extract relaxed the spontaneous and high K