Observation of tear film stability in dry eye patients with different lipid layer thickness
10.3980/j.issn.1672-5123.2023.5.29
- VernacularTitle:不同脂质层厚度干眼患者泪膜稳定性的观察研究
- Author:
Peng ZHANG
1
;
Kun-Ling HAN
1
;
Yan-Zheng WANG
1
;
Yan-Ling WANG
1
Author Information
1. Department of Cataract, Han Dan City Eye Hospital(The Third Hospital OF HanDan), Handan 056001, Hebei Province, China
- Publication Type:Journal Article
- Keywords:
tear film;
lipid layer;
dry eye;
tear meniscus height;
tear film break-up time
- From:
International Eye Science
2023;23(5):864-866
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To explore the difference of tear film stability among different lipid layer thickness.METHOD: A total of 194 dry eye patients(384 eyes)admitted to our hospital from June 2020 to December 2021 were enrolled in this study. The tear meniscus height, the first tear film break-up time and lipid layer thickness were measured by corneal topographer. The tear meniscus height and the first tear film break-up time among different lipid layer thickness were compared and the correlation between them was analyzed.RESULTS: The included patients(384 eyes)were divided into lipid rich group(49 eyes), lipid balance group(27 eyes), slight lipid deficiency group(266 eyes)and significant lipid deficiency group(42 eyes)according to the lipid layer thickness. The differences of the tear meniscus height were statistically different(P=0.022), while the differences of the first tear film break-up time were not statistically different(P=0.322). The lipid layer thickness was positively correlated with tear meniscus height(rs=0.143, P=0.006). There was no correlation between lipid layer thickness and the first tear film break-up time(rs=-0.090, P=0.083), nor was there correlation between tear meniscus height and the first tear film break-up time(rs=0.038, P=0.460).CONCLUSION: There was no significant difference in tear film stability in dry eye patients with different lipid layer thickness.
