Effects of low-energy red light on choroidal thickness and spherical equivalent and axial length in myopic children
10.3980/j.issn.1672-5123.2023.5.15
- VernacularTitle:低能量红光对近视儿童脉络膜厚度和等效球镜度及眼轴长度的影响
- Author:
Zhi-Ming GU
1
,
2
,
3
;
Chang-Jun LAN
1
,
2
,
3
;
Wei-Qi ZHONG
1
,
2
,
3
;
Gui-Mei ZHOU
1
,
2
,
3
;
Xuan LIAO
1
,
2
,
3
Author Information
1. Department of Ophthalmology, Affiliated Hospital of North Sichuan Medical College, Nanchong 637000, Sichuan Province, China
2. Medical School of Ophthalmology &
3. Optometry, North Sichuan Medical College, Nanchong 637000, Sichuan Province, China
- Publication Type:Journal Article
- Keywords:
red light;
myopia;
choroidal thickness;
spherical equivalent;
axial length;
Meta-analysis
- From:
International Eye Science
2023;23(5):791-796
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To systematically evaluate the effects of low-energy red light on choroidal thickness(ChT), spherical equivalent(SE), and axial length(AL)in myopic children.METHODS: A total of 8 databases, including Pubmed, Embase, Cochrane Library, Web of Science, CNKI, WanFang Database, VIP Database and China Biomedical Literature Database, were electronically retrieved to collect the clinical randomized controlled trial(RCT)of low-energy red light in myopia, with red light intervention as an experimental group and glasses as a control group. The retrieval time limit is from the establishment of the database to January 2023. According to the recommendation of the Cochrane Handbook, literature quality and risk of bias were evaluated. Revman5.4 software was used for Meta-analysis.RESULTS: Totally 8 RCT about red-light treatment with myopia were included. The sample size for ChT analysis contained 407 eyes in the red-light group and 425 eyes in the control group; SE analysis included 490 eyes in the red-light group and 518 eyes in the control group; sample size for AL analysis were 518 eyes in the red-light group and 539 eyes in the control group. The differences in ChT, SE and AL between the groups were statistically significant(ChT: WMD=37.81, 95%CI: 21.55～54.07, P<0.001; SE: WMD=0.58, 95%CI: 0.46～0.71, P<0.001; AL: WMD=-0.31, 95%CI: -0.39～-0.24, P<0.001).CONCLUSION: Specific red light can promote the increase of ChT while inhibit SE and AL. However, its long-term efficacy and side effects remain unclear. The above conclusions need to be further clarified by more RCT with large samples.
