Research progress of tradition Chinese medicine treatment mechanism of systemic lupus erythematosus based on biomarkers
10.12206/j.issn.2097-2024.202206131
- VernacularTitle:基于生物标志物探索系统性红斑狼疮中医药治疗机制的研究进展
- Author:
Yaoyang LIU
1
;
Xin WU
1
;
Ling ZHOU
1
;
Ying ZHAO
2
;
Huji XU
1
Author Information
1. Department of Rheumatology and Immunology, Changzheng Hospital, Naval Medical University, Shanghai 200003, China.
2. Department of Traditional Chinese Medicine, Changzheng Hospital, Naval Medical University, Shanghai 200003, China.
- Keywords:
biomarkers;
systemic lupus erythematosus (SLE);
traditional Chinese medicine;
metabonomic;
immune cells;
cytokines
- From:
Journal of Pharmaceutical Practice
2023;41(4):197-201
- CountryChina
- Language:Chinese
-
Abstract:
Systemic lupus erythematosus (SLE) is an autoimmune disease with multiple organ involvement. There are still many limitations and individual differences in the treatment based on glucocorticoids and immunosuppressants. In recent years, more and more studies have shown that the combination of traditional Chinese medicine in the treatment of SLE has the advantages of good efficacy, low adverse reactions, and high safety. However, the exact regulatory mechanism and combined traditional Chinese medicine in the treatment of SLE are still unclear. This paper reviews the research on the mechanism of traditional Chinese medicine in the treatment of SLE from metabonomic, immune cells, lymphocyte factors and apoptosis, etc, provides ideas for exploring the mechanism of traditional Chinese medicine in the treatment of SLE with modern methods.
