Correlation between N-terminal Pro-brain Natriuretic Peptide and Cardiac Diastolic and Systolic Function
- VernacularTitle:脑型利尿钠肽前体氨基端肽与心脏舒缩功能的相关性研究
- Author:
Yi CAI
;
Li FAN
;
Kunlun HE
;
Lihui YAN
;
Wenxiu LENG
- Publication Type:Journal Article
- Keywords:
N-terminal pro-brain natriuretic peptide (NT-proBNP), cardiac function, echocardiography
- From:
Chinese Journal of Rehabilitation Theory and Practice
2009;15(11):1021-1023
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the correlation between N-terminal pro-brain natriuretic peptide (NT-proBNP) and cardiac diastolic and systolic function. Methods 60 New Zealand male rabbits were randomly assigned to two groups. The abdominal aorta 1 cm just above right renal artery were constricted in operated group. The clinical manifestation of heart failure was observed, and cardiac structure and function were investigated with echocardiography. Concentration of serum NT-proBNP was determined regularly. Results The concentration of NT-proBNP was correlated with Sm（r=－0.635,P=0.000）, Em（r=－0.693,P=0.000）, E/Em（r=0.688,P=0.000）, E/Vp（r=0.707, P=0.000）, and EF（r=－0.395,P=0.001）. Conclusion Concentration of serum NT-proBNP could prognose the diastolic and long axis systolic function of left ventricle.
