Releasing Spasticity of Triceps Surae Muscle of Children with Spastic Cerebral Palsy by Botulinum Toxic A Block with Dose Calculated According to Certain Formula
- VernacularTitle:应用公式计算A型肉毒毒素剂量缓解脑瘫小腿三头肌痉挛的对照研究
- Author:
Jianjun LIU
;
Shurong JI
;
Yingyuan HU
;
Weihong WU
;
Chunyan LI
;
Huabao LU
;
Yan ZHANG
- Publication Type:Journal Article
- Keywords:
cerebral palsy, spasticity, botulinum toxic A, nerve block, dose
- From:
Chinese Journal of Rehabilitation Theory and Practice
2008;14(10):956-957
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate whether the curative effect of Botulinum Toxic A(BTX-A) block increased and prolonged when the dose calculated according to certain formula.Methods 15 children with cerebral palsy(CP) were appointed as the trial group and the dose of BTX-A was calculated according to the designed formula.The other 58 CP children were appointed as the control group and the BTX-A dose was determined by routine method.Results After treatment,the motor function of the children in trial group was superior to that in the control group(P<0.05) and the duration of therapeutic effect of the trial group was significantly longer than the control group(P<0.001).Conclusion BTX-A dose calculated according to the formula can increase effect and prolong the duration.