Relationship between Plasma Total Homocysteine and Carotid Atherosclerosis in Hypertentive Patients
- VernacularTitle:高血压患者血浆同型半胱氨酸水平与颈动脉粥样硬化的关系
- Author:
Hong WANG
;
Xiangyang ZHANG
;
Ying ZHANG
;
Meisheng ZHU
;
Ailun ZHANG
;
Xiaohui ZHOU
- Publication Type:Journal Article
- Keywords:
hypertension, homocysteine, carotid atherosclerosis, carotid intima-media thickness
- From:
Chinese Journal of Rehabilitation Theory and Practice
2008;14(8):751-753
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the level of plasma total homocysteine(Hcy),the carotid intima-media thickness(IMT)and relationship of the plasma Hcy and carotid atherosclerosis in hypertensive patients.Methods Sixty patients with hypertension and sixty health controls were measured for carotid IMT and the level of plasma total Hcy.Results The level of plasma total Hcy and the carotid IMT in hypertensive patients increased significantly compared with that of the controls.The level of plasma total Hcy increased with the severity of the carotid plaque.The carotid IMT was correlated with age,cholesterol,low-density cholesterol,systolic blood pressure(P<0.05 or P<0.01).Conclusion The average carotid IMT is correlated with the level of plasma Hcy in hypertensive patients;the level of plasma total Hcy,age,cholesterol,low-density cholesterol,systolic blood pressure are the important risk factors of carotid atherosclerosis.
